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Table 3 Changes of outcome measures with each outcome group.

From: Diagnosis of idiopathic normal pressure hydrocephalus is supported by MRI-based scheme: a prospective cohort study

 

Baseline

12 months

p value*

INPHGS gait score

   

   All patients

2 (2.3-2.6)

1 (1.2-1.7)

< 0.001

   Favorable outcome

2 (2.3-2.6)

1 (0.8-1.3)

< 0.001

   Unfavorable outcome

2 (2.1-2.7)

2 (1.9-2.8)

ns

iNPHGS cognitive score

   

   All patients

2 (2.1-2.4)

1 (1.3-1.7)

< 0.001

   Favorable outcome

2 (2.0-2.5)

1 (1.0-1.5)

< 0.001

   Unfavorable outcome

2 (1.8-2.6)

2 (1.6-2.4)

ns

iNPHGS urinary score

   

   All patients

2 (1.7-2.2)

1 (0.8-1.3)

< 0.001

   Favorable outcome

2 (1.5-2.1)

1 (0.5-0.9)

< 0.001

   Unfavorable outcome

2 (1.8-2.8)

2 (1.4-2.4)

ns

iNPHGS total score

   

   All patients

6 (6.1-7.1)

4 (3.4-4.6)

< 0.001

   Favorable outcome

6 (5.9-7.1)

2 (2.4-3.6)

< 0.001

   Unfavorable outcome

6 (5.9-7.9)

5 (5.1-7.5)

ns

Timed "up & go" test (seconds)

  

   All patients

20.5 (16-30)

14 (11-20)

< 0.001

   Favorable outcome

20 (16.5-28)

13 (10-17)

< 0.001

   Unfavorable outcome

22 (15-41)

20 (13-33)

0.004

MMSE

   

   All patients

23 (16.3-26)

25 (20.3-28)

< 0.001

   Favorable outcome

23 (15.5-26)

25 (21.5-28)

< 0.001

   Unfavorable outcome

23 (17-25)

24 (16-27)

ns

  1. Data are median (75th percentile).
  2. * All p values were obtained using Wilcoxon test. ns: not significant.
  3. iNPHGS: Idiopathic Normal-Pressure Hydrocephalus Grading Scale, MMSE:Mini-Mental State Examination.