Table 3 Summarized results and statistical comparisons
From: Congenital myelomeningocele - do we have to change our management?
| Â | (1) Leipzig group | (2) IUMR group | (3) Historical controls | Statistical comparison (p-value) | ||
|---|---|---|---|---|---|---|
| Â | Â | Â | Â | (2) vs (3) | (1) vs (2) | (1) vs (3) |
Neonatal death (%) | 0 | 4.5 [21] | NA | - | < 0.05 | - |
GA at birth (wk) | 37.8 ± 2.3 | 34.6 [21] | 37.0 [22] | - | < 0.0001 | ns |
| Â | Â | 33.2 [22] | 37.0 [22] | < 0.001 [22] | - | - |
GA < 30th wk (%) | 0 | 11.8 [23] | NA | - | < 0.05 | - |
Birth weight (g) | 2921.3 ± 760.3 | 2512 [24] | 3075 [22] | - | < 0.01 | ns |
| Â | Â | 2171 [22] | 3075 [22] | < 0.001 [22] | - | - |
Shunt placement ≤ 1 y (%) | 69.8 | 54.3 [25] | 85.7 [21] | < 0.0001 | ns | < 0.05 |
Age at shunt placement (d) | 16.0 ± 10.7 | 21.2 [24] | - | - | < 0.05 | - |
| Â | 12.5$ | 85.5 [22]$ | 5 [28]$ | < 0.01 [22] | - | - |
Incidence ACM II (%) | 57.1 | 100§ | 75.7 [15] | - | - | ns |
Surgery TC (%) | 11.1 | 29.6 [26] | 32.4 [5] | ns | < 0.01 | < 0.001 |
(Assisted) Walkers (%) | 56.4£ | 92.6 [18]# | 59.2 [5]¶ | < 0.0001 | < 0.0001 | ns |
Wheelchair users (%) | 41.0£ | 7.4 [18]# | 40.8 [5]¶ | < 0.0001 | < 0.0001 | ns |
Regular education (%) | 64.1 | NA | 63.4 [5] | - | - | ns |
CIC (%) | 69.7 | NA | 84.5 [5] | - | - | ns |