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Figure 2 | Cerebrospinal Fluid Research

Figure 2

From: Co-localization and regulation of basic fibroblast growth factor and arginine vasopressin in neuroendocrine cells of the rat and human brain

Figure 2

Co-localization of FGF2 and AVP in human brain: (A) FGF2 immunoreactivity was found within human magnocellular neurons and their processes (arrowheads). FGF2 immunostain was observed within endothelium of cerebral vessels (arrows) and in astrocytes and their processes (bar = 50 μm). (B) Note AVP immunoreactivity within neuronal perikarya and processes (arrowheads) of magnocellular neurons in the PVN of adult human hypothalamus. Axons are clearly distinguishable because their 'beaded' structure (bar = 50 μm). (C) Composite-merged image of FITC-stained anti-AVP and LRSC-stained anti-FGF2 immunoreactivities generated from 46 sequential 0.2 μm slices at 200X. Co-localization of FITC-labeled AVP and LRSC-labeled FGF2 immunoreactivities was confirmed by yellow fluorescence. Yellow fluorescence occurs in varying degrees in nearly all magnocellular neurons (arrowheads). Some red LRSC-stained structures lacking yellow fluorescence are probably astrocytes with processes (arrow).

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