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Table 3 Chronic and acute white matter lesion volumes as predictors for APP metabolites in all patients.

From: Effects of cerebrovascular disease on amyloid precursor protein metabolites in cerebrospinal fluid

Dependent Variables

Independent variables p (beta)

 

cWML

aWML

Age

CSF sAPP-α

≤0.005

n.s.

n.s.

 

(-0.396)

  

CSF sAPP-β

≤0.01

n.s.

n.s.

 

(-0.369)

  

CSF AβX-38

≤0.01

n.s.

≤0.01

 

(-0.359)

 

(0.371)

CSF AβX-40

≤0.05

n.s.

≤0.05

 

(-0.357)

 

(0.309)

CSF AβX-42

≤0.05

n.s.

n.s.

 

(-0.273)

  
  1. Chronic WML significantly predicts CSF levels of APP metabolites.
  2. cWML = chronic WML, aWML = acute WML.
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Fluids and Barriers of the CNS

ISSN: 2045-8118