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Table 1 Summary of relative changes in expression of A-beta protein (Aβ), low-density lipoprotein receptor-related protein (LRP-1), receptor for advanced glycation end products (RAGE) and glial fibrillary acidic protein (GFAP) in brain tissue from control and hydrocephalic rats.

From: Low levels of amyloid-beta and its transporters in neonatal rats with and without hydrocephalus

 

Adult

Hydro vs. Control

IHC

Neonatal

Hydro vs. Control

IHC/qRT-PCR

Adult Control

vs.

Neonatal Control

IHC

Adult Hydro

vs.

Neonatal Hydro

IHC

Aβ

Increase

NC/NA

NC

Decrease

LRP-1

Decrease

NC/NC

Decrease

NC

RAGE

Increase

NC/NC

Decrease

Decrease

GFAP

Increase

Increase/Increase

NC

NC

  1. IHC: immunohistochemistry; qRT-PCR: quantitative RT- PCR; NC- no change; NA-not applicable. Results from cortex and hippocampus have been combined.