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Table 1 List of drugs used

From: Activation of adenosine A2B receptors enhances ciliary beat frequency in mouse lateral ventricle ependymal cells

Abbreviation

Full Name

Site of Action*

αβmADP

Adenosine 5'-(α,β-methylene)diphosphate

Ecto-5'-nucleotidase inhibitor

Adenosine

9-β-D-Ribofuranosyladenine

Nonselective adenosine receptor agonist

ATP

Adenosine 5'-triphosphate

P2 purinergic agonist

BBG

Brilliant blue G

P2X7 receptor antagonist

BzATP

2'(3')-O-(4-benzoylbenzoyl)adenosine 5'-triphosphate triethylammonium salt

P2X purinergic agonist; more potent than ATP at P2X7 receptors

CGS-21680

4-[2-[[6-Amino-9-(N-ethyl-b-D-ribofuranuronamidosyl)-9H-purin-2-yl]amino]ethyl]benzenepropanoic acid hydrochloride

A2A adenosine receptor agonist

Dipyridamole

2,6-Bis(Diethanolamino)-4,8-dipiperidinopyrimido [5,4-d] pyrimidine

Equlibrative nucleoside transporter inhibitor

IB-MECA

1-Deoxy-1-[6-[[(3-iodophenyl)methyl]amino]-9H-purin-9-y l]-N-methyl-b-D-ribofuranuronamide

Selective A3 adenosine receptor agonist

2'MeCCPA

2-Chloro-N-cyclopentyl-2'-methyladenosine

Selective A1 adenosine receptor agonist

MRS 1754

N-(4-cyanophenyl)-2-[4-(2,3,6,7-tetrahydro-2,6-dioxo-1,3-dipropyl-1H-purin-8-yl)phenoxy]-acetamide

Selective adenosine A2B receptor antagonist

NBMPR

S-(4-Nitrobenzyl)-6-thioinosine

Equilibrative nucleoside transporter 1 inhibitor

NECA

5'-N-ethylcarboxamidoadenosine

Nonselective adenosine receptor agonist.

Phloridzin

Phloretin 2'-β-D-glucopyranoside

Concentrative nucleoside transporter inhibitor

PSB 603

8-[4-[4-(4-Chlorophenzyl)piperazide-1-sulfonyl)phenyl]]-1-propylxanthine

Selective adenosine A2B receptor antagonist

Suramin

8,8'-[Carbonylbis[imino-3,1-phenylenecarbonylimino(4-me thyl-3,1-phenylene)carbonylimino]]bis-1,3,5-naphthalene trisulfonic acid hexasodium salt

P2 antagonist (with broad subtype selectivity)

UTP

Uridine 5'-triphosphate

P2Y2/P2Y4 receptor agonist

  1. * Selectivity depends on the concentration tested. Non-purinergic activities may also be present.