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Figure 8 | Cerebrospinal Fluid Research

Figure 8

From: The morphology and biochemistry of nanostructures provide evidence for synthesis and signaling functions in human cerebrospinal fluid

Figure 8

Immuno-TEM of ultrastructures from P3 fractions of CSF, representative of sample #s 4-19. The 12 and 18 nm gold particles are visible in all structures, specific for the eight antisera tested (negative controls with pre-immune sera only had occasional random gold particles): Nanospheres are specifically labeled with A: prostaglandin H synthase 2; B, D, H: ras-related protein Ral-A; C: ADP-ribosylation factor-like protein 2; E: synaptosomal-associated protein 23; F: secretogranin 3; and G: acetylcholine. Nanostrands and nanoblobs are labeled with J: secretogranin 3; K: 3-oxo-5-alpha-steroid 4-dehydrogenase; and L, M: fibronectin. Scale bars 100 nm.

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Fluids and Barriers of the CNS

ISSN: 2045-8118