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Table 1 Clinical data

From: Pathogenesis of cerebral malformations in human fetuses with meningomyelocele

Case

GA

MMC

Malformations

Delivery induction

Time

Recent acute bleedings

   

cerebralaa

non-CNS

 

induction-delivery

 

1

16

C-Th

holopros.; fused basal ganglia; cortical dysplasia

palatoschisis annular pancreas atresia ani scoliose

PG

< 1 day

PF

2

21

L-S

-

reduction defect of extremity

PG

< 1 day

IVH, SAH, PF

3

21

Th-L

-

single umbilical artery

PG

< 1 day

IVH, SAH

4

22

L-S

-

dysplasia costae kyfose

PG

< 0.5 day

PF

5

34

Th-L

-

OEIS complex pes calcaneovalgus lung hypoplasia kyphosis

abruption placentae

ni

IVH

6

37

L-S

-

-

cephalocentesis

< 1 day

IVH, SAH, PF

7

39

L-S

agenesis of: cerebellum, nucleus olivaris inferior, and pontine nuclei

pes calcaneovalgus finger-malformation

VE

ni

IVH, PF

8

40

Th-L

hypoplasia of cerebellum

palatoschisis pes calcaneovalgus ASD

cephalocentesis

< 1 day

IVH, SAH

  1. Legends: GA = gestational age in weeks, MMC = segmental level of the meningomyelocele, acerebral malformations other than ventriculomegaly and Chiari malformation, holopros. = holoprosencephaly, non-CNS = outside the central nervous system, C = cervical, Th = thoracal, L = lumbar, S = sacral, - = absent, OEIS complex = Omphalocele, Exstrophy, Imperforate anus, Spinal defects, ASD = atrium septum defect, PG = prostaglandin, VE = vacuum extraction, Time induction-delivery = time between induction and delivery, ni = no induction, PF = fossa posterior, IVH = intraventricular bleeding, SAH = subarachnoidal hemorrhage.