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Fluids and Barriers of the CNS
Table 4 CSF dynamics and volume in aging and neurodegeneration
Multiplicity of cerebrospinal fluid functions: New challenges in health and disease
CSF Formation Rate (ml/min)
CSF Volume (space) (ml)
CSF Turnover Rate (volumes/day)
CSF formation rate and volume in rats were determined by indicator dilution during ventriculo-cisternal perfusion . CSF turnover rate = formation rate/volume.
CSF formation rate and volume in patients were quantified by a modified Masserman technique . NPH, normal pressure hydrocephalus; AD, Alzheimer's disease.
Volumes/day = the number of times each day that the entire CSF volume is renewed.
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