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Table 3 Neuropeptides/receptors that regulate CSF formation

From: Multiplicity of cerebrospinal fluid functions: New challenges in health and disease

 

ANP

AVP

ANG II

FGF2

Effect on CSF formation after i.c.v. administration of neuropeptide [84, 87, 178, 217]

↓

↓

↓

↓

Peptidergic effect on choroidal blood flow [84, 139]

↑

↓

↓

N/A*

Inducer of neuro-endocrine-like dark epithelial cells in choroid plexus? [82, 83, 178]

Yes

Yes

N/A

Yes

Choroid epithelial receptors for peptides [83, 85, 103, 211, 217]

NPR-A

V1

AT1

FGFR2

Concentration of peptide in CSF in hydrocephalus or increased ICP [98–100, 104]

↑

↑

N/A

N/A

  1. * N/A: Data are not available.