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Table 1 Treatment data on patients treated with irinotecan, thalidomide, and doxycycline

From: Cerebrospinal fluid matrix metalloproteinase-9 increases during treatment of recurrent malignant gliomas

Patient Age Histology Number of Cycles TTPa OSa
1 61 anaplastic oligodendroglioma 4 6 months 17+ months
2 67 glioblastoma multiforme 3 4 months 10 months
3 54 anaplastic astrocytoma 1 N/A 5 month
4 34 anaplastic oligodendroglioma 2 N/A 8 months
  1. aTTP = time to tumor progression; OS = overall survival