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Table 1 Treatment data on patients treated with irinotecan, thalidomide, and doxycycline

From: Cerebrospinal fluid matrix metalloproteinase-9 increases during treatment of recurrent malignant gliomas

Patient

Age

Histology

Number of Cycles

TTPa

OSa

1

61

anaplastic oligodendroglioma

4

6 months

17+ months

2

67

glioblastoma multiforme

3

4 months

10 months

3

54

anaplastic astrocytoma

1

N/A

5 month

4

34

anaplastic oligodendroglioma

2

N/A

8 months

  1. aTTP = time to tumor progression; OS = overall survival