Figure 5

Scanning densitometry analysis of Western blots for GFAP in the occipital cortex: histogram of relative density. There was an increase in GFAP levels with hydrocephalus at all ages, although at 12d it was not significant. There was a significant increase over control at 5d, 21d and at 36d. In the shunted groups, GFAP was significantly reduced from untreated hydrocephalus by 76.9% at 21d and by 48.2% at 36d. Single asterisks indicates statistical significance at p < 0.05, double asterisk indicates significance at p < 0.01, brackets indicate comparison group. N = 5 for each group, values are means +/- standard deviation.