Table 1 Physiologic parameters during rabbit spinal cord ischemia. Values are mean ± SD. Baseline physiological values were determined 5 minutes before cross-clamping the aorta. Reperfusion physiological values were determined 5 minutes after releasing the clamp around abdominal aorta. None of the physiological parameters at baseline and reperfusion differed significantly between the various experimental groups. There were no significant differences in MBP, PO2, PCO2 and glucose between baseline and reperfusion in any group. The pH value was slightly decreased after ischemia in each group, however, there were no significant differences either.
| Â | Group | ||||||
|---|---|---|---|---|---|---|---|
| Â | 1 | 2 | 3 | 4 | 5 | 6 | 7 |
Variable | n = 10 | n = 10 | n = 10 | n = 10 | n = 10 | n = 10 | n = 7 |
MAP (mmHg) | |||||||
   Baseline | 82 ± 12 | 83 ± 11 | 86 ± 12 | 76 ± 7 | 84 ± 14 | 79 ± 11 | 81 ± 15 |
   Reperfusion | 80 ± 8 | 81 ± 11 | 81 ± 10 | 76 ± 11 | 78 ± 14 | 74 ± 11 | 73 ± 9 |
pH | |||||||
   Baseline | 7.40 ± 0.03 | 7.41 ± 0.03 | 7.40 ± 0.03 | 7.39 ± 0.02 | 7.39 ± 0.02 | 7.40 ± 0.03 | 7.40 ± 0.03 |
   Reperfusion | 7.35 ± 0.02 | 7.34 ± 0.03 | 7.35 ± 0.05 | 7.34 ± 0.03 | 7.35 ± 0.04 | 7.33 ± 0.02 | 7.33 ± 0.03 |
PaO2 (mmHg) | |||||||
   Baseline | 212 ± 19 | 221 ± 18 | 225 ± 24 | 208 ± 22 | 213 ± 20 | 226 ± 18 | 223 ± 24 |
   Reperfusion | 225 ± 26 | 209 ± 20 | 223 ± 20 | 212 ± 20 | 225 ± 21 | 230 ± 14 | 234 ± 31 |
PaCO2 (mmHg) | |||||||
   Baseline | 38 ± 3 | 37 ± 4 | 38 ± 2 | 37 ± 3 | 39 ± 2 | 37 ± 2 | 37 ± 3 |
   Reperfusion | 35 ± 7 | 35 ± 3 | 36 ± 5 | 35 ± 5 | 36 ± 3 | 35 ± 4 | 34 ± 5 |
Glucose (mg/dl) | |||||||
   Baseline | 131 ± 22 | 133 ± 27 | 123 ± 26 | 128 ± 29 | 141 ± 25 | 121 ± 30 | 126 ± 25 |
   Reperfusion | 134 ± 22 | 143 ± 25 | 117 ± 24 | 138 ± 30 | 144 ± 25 | 128 ± 26 | 135 ± 30 |