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Figure 3 | Cerebrospinal Fluid Research

Figure 3

From: In normal rat, intraventricularly administered insulin-like growth factor-1 is rapidly cleared from CSF with limited distribution into brain

Figure 3

Plasma radioactivity over time after infusions into the lateral ventricle and parenchyma. Data are shown as mean ± SD. Plasma concentrations were fairly similar for both infusions up to 20 min, when the intraventricular infusion began to yield higher radioactivity; plasma concentrations for intraventricular infusions were about 50% higher than those for intraparenchymal infusion at 90–180 min. These data plus those in Fig. 2 clearly show the much greater clearance of intraventricularly infused 125I-IGF-1.

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