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Table 1 Mean and SD of IgG index, local IgG synthesis (Igloc) and antibody index (AI) for measles, rubella and varicella zoster virus at each successive lumbar puncture (LP). The number of patients in each category of serial LP is given. All included patients received at least two serial LPs (first and second). Additional LPs were only obtained in the mentioned number of patients.

From: Expansion of antibody reactivity in the cerebrospinal fluid of multiple sclerosis patients – follow-up and clinical implications

LP no.

No. of patients with the respective LP

IgG index

Igloc (mg/L)

AI measles

AI rubella

AI varicella zoster

1.

70

1.3 ± 0.75

33 ± 5,0

3.4 ± 3.29

4.6 ± 7.11

3.6 ± 5.86

2.

70

1.3 ± 1.58

25 ± 4,1

3.5 ± 3.67

4.8 ± 7.67

3.6 ± 5.85

3.

26

1.4 ± 0.99

46 ± 1,1

3.9 ± 5.59

5.4 ± 9.28

4.7 ± 7.28

4.

12

1.2 ± 0.73

28 ± 0,9

2.8 ± 2.09

6.7 ± 14.78

4.4 ± 8.74

5.

7

1.0 ± 0.39

19 ± 4,8

2.1 ± 0.89

1.9 ± 1.28

1.9 ± 1.46