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Figure 2 | Cerebrospinal Fluid Research

Figure 2

From: Genetic loci for ventricular dilatation in the LEW/Jms rat with fetal-onset hydrocephalus are influenced by gender and genetic background

Figure 2

LOD score graphs created from the MAPMAKER output for [(F × L) × L], B rats on chromosomes 5 and 19. The X-axes represent the recombination distance in centi-Morgans (cM). The microsatellite markers are positioned on the X-axis and named below. The horizontal dotted line represents the score required for suggestive significance (1.9). a: Plot for male B rats on Chr 5 and b: plot for female B rats (solid lines), dotted line represents a portion of the plot for both sexes combined, where the LOD score (1.94) reached suggestive significance. There was a strong female bias (3b). c: Plot for male B rats on Chr 19 and d: plot for female rats (solid lines). The dotted line near the centromeric end represents part of the plot for both sexes combined where the LOD score (1.89) is very close to suggestive significance for linkage. The male rats contributed to this peak almost exclusively.

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