Gerald Silverberg, Editorial Board Member
Stanford University, USA
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I did my undergraduate degree at Dartmouth College, obtaining an AB in 1959. I graduated from Stanford University School of Medicine in 1964. I did my neurosurgery training at Stanford, finishing in 1973. I joined the Neurosurgery faculty at Stanford that year, rising to the rank of Professor. During my tenure at Stanford I enjoyed a busy clinical practice focused primarily on cranial surgery for aneurysms, AVMs and tumors. My research interests included the use of hypothermia and cardiac arrest in the surgical management of giant aneurysms. In my research laboratory, I worked on defining the neurogenic and metabolic control of the cerebral circulation at the smooth muscle cell level, using single electrode voltage clamping of isolated arteriolar smooth muscle cells in rats. While at Stanford I helped to develop the Epilepsy Center and the Movement Disorders Clinic.
I retired from Stanford in 2004. I returned to research work at the Warren Alpert Medical School, Brown University in the Department of Neurosurgery that same year. In my research laboratory I am presently studying the effects of aging on the brain, with an emphasis on how aging changes in the brain barrier expression of the amyloid transporter proteins causes amyloid accumulation in the brain parenchyma, and how alterations in the production and turnover of CSF with age relates to Alzheimer’s disease and NPH. Our research laboratory is funded by NIH and private foundations. Over the years I have enjoyed the privilege of serving on the board and as president of the California Association of Neurological Surgeons, the San Francisco Neurological Society and the Western Neurosurgical Society.