Fig. 4

Reduced turbinate tracer input and egress in amyloid positive subjects. TACs from 0 to 60 min (3,600 s) following [1-¹¹C]-Butanol administration. The Y-axis SUV is the radiotracer concentration normalized by dose and weight for: (A) LOF cortex and (B) All-turbinates. The LOF Repeated Measures Two-Way ANOVA showed a main effect of Aβ subgroup (F(1,22) = 4.587, p = 0.0435) and Aβ subgroup by time interaction (F(359,7898) = 1.453, p < 0.0001). Similarly, the All-turbinates showed a significant main effect for Aβ subgroup (F(1,22) = 11.29, p = 0.0023) and the Aβ subgroup by time interaction (F(359, 7898) = 6.684, p < 0.001)