From: Usefulness of intravoxel incoherent motion MRI for visualizing slow cerebrospinal fluid motion
Region of interest | Healthy volunteer | iNPH patient (36) | P-valuea | P-valueb | ||
---|---|---|---|---|---|---|
 < 40 years (47) | 40–59 years (49) | 60 <  = years (36) | ||||
Lt. lateral ventricle (anterior horn) | 43.2 ± 18.6 | 44.0 ± 12.4 | 48.9 ± 19.1 | 23.9 ± 7.8 |  < 0.001 | 0.274 |
Rt. lateral ventricle (anterior horn) | 43.0 ± 17.4 | 46.9 ± 12.0 | 53.8 ± 16.7 | 24.5 ± 8.0 |  < 0.001 | 0.017 |
Lt. lateral ventricle (body) | 35.4 ± 14.8 | 33.8 ± 13.7 | 29.4 ± 16.5 | 19.9 ± 6.3 |  < 0.001 | 0.028 |
Rt. lateral ventricle (body) | 39.2 ± 15.3 | 32.0 ± 11.7 | 27.3 ± 15.7 | 21.7 ± 6.2 | 0.108 |  < 0.001 |
Lt. lateral ventricle (trigon) | 52.8 ± 15.0 | 53.4 ± 12.6 | 58.8 ± 12.2 | 29.4 ± 13.4 |  < 0.001 | 0.164 |
Rt. lateral ventricle (trigon) | 53.6 ± 15.0 | 52.9 ± 10.0 | 58.6 ± 14.0 | 31.1 ± 11.3 |  < 0.001 | 0.112 |
Lt. lateral ventricle (inferior horn) | 58.0 ± 13.1 | 56.3 ± 12.5 | 64.2 ± 11.5 | 36.9 ± 12.1 |  < 0.001 | 0.014 |
Rt. lateral ventricle (inferior horn) | 58.1 ± 11.8 | 56.8 ± 11.1 | 66.4 ± 7.6 | 39.0 ± 12.2 |  < 0.001 |  < 0.001 |
Lt. foramen of Monro | 75.1 ± 13.2 | 78.0 ± 10.4 | 79.6 ± 7.9 | 69.2 ± 16.9 | 0.005 | 0.419 |
Rt. foramen of Monro | 72.0 ± 13.3 | 76.0 ± 10.1 | 78.1 ± 10.8 | 67.6 ± 18.2 | 0.008 | 0.041 |
3rd ventricle (anterior part) | 81.2 ± 9.8 | 81.5 ± 11.2 | 76.1 ± 20.1 | 48.2 ± 25.6 |  < 0.001 | 0.755 |
3rd ventricle (posterior part) | 82.5 ± 6.9 | 83.7 ± 6.8 | 84.6 ± 6.2 | 80.3 ± 8.1 | 0.026 | 0.235 |
Cerebral aqueduct | 69.1 ± 11.1 | 68.0 ± 13.5 | 74.4 ± 9.0 | 74.6 ± 8.7 | 0.955 | 0.026 |
4th ventricle (upper part) | 75.1 ± 7.2 | 73.1 ± 8.3 | 78.0 ± 5.8 | 75.7 ± 8.2 | 0.277 | 0.015 |
4th ventricle (middle part) | 50.2 ± 15.9 | 49.7 ± 16.1 | 58.9 ± 17.6 | 54.2 ± 18.5 | 0.224 | 0.027 |
4th ventricle (lower part) | 61.6 ± 12.1 | 61.3 ± 15.5 | 62.3 ± 14.5 | 67.1 ± 13.3 | 0.096 | 0.871 |
Lt. foramen of Luschka | 49.3 ± 12.3 | 48.2 ± 10.5 | 57.8 ± 14.4 | 66.6 ± 14.1 | 0.004 | 0.001 |
Rt. foramen of Luschka | 46.3 ± 8.9 | 46.1 ± 10.6 | 58.5 ± 12.6 | 69.0 ± 10.0 |  < 0.001 |  < 0.001 |
Foramen of Magendie | 74.6 ± 8.4 | 75.3 ± 9.6 | 78.3 ± 7.4 | 78.0 ± 7.5 | 0.698 | 0.116 |
Foramen magnum | 75.7 ± 12.3 | 69.0 ± 14.4 | 77.7 ± 11.8 | 62.7 ± 20.7 |  < 0.001 | 0.008 |
Lt. cerebellopontine angle | 84.1 ± 8.2 | 85.5 ± 6.4 | 85.9 ± 6.9 | 80.3 ± 10.8 | 0.023 | 0.523 |
Rt. cerebellopontine angle | 83.8 ± 8.2 | 86.5 ± 7.0 | 88.0 ± 5.6 | 79.2 ± 11.8 |  < 0.001 | 0.022 |
Prepontine cistern | 88.5 ± 3.9 | 87.6 ± 3.5 | 88.4 ± 3.2 | 87.1 ± 6.1 | 0.719 | 0.359 |
Suprasellar cistern | 89.7 ± 4.7 | 90.2 ± 2.6 | 89.9 ± 3.7 | 83.9 ± 12.6 | 0.006 | 0.952 |
Interhemispheric fissure (lower part) | 80.9 ± 8.1 | 82.8 ± 7.0 | 85.3 ± 6.3 | 78.9 ± 13.1 | 0.011 | 0.033 |
Quadrigeminal cistern | 68.0 ± 11.9 | 73.0 ± 9.4 | 71.4 ± 15.5 | 60.2 ± 16.4 | 0.001 | 0.081 |
Lt. ambient cistern | 82.4 ± 9.5 | 84.9 ± 4.2 | 86.8 ± 5.4 | 71.5 ± 15.3 |  < 0.001 | 0.013 |
Rt. ambient cistern | 83.2 ± 8.7 | 84.5 ± 5.6 | 88.6 ± 3.9 | 73.0 ± 15.0 |  < 0.001 |  < 0.001 |
Lt. carotid cistern | 89.3 ± 4.2 | 89.3 ± 4.8 | 91.9 ± 1.9 | 86.1 ± 7.7 |  < 0.001 |  < 0.001 |
Rt. carotid cistern | 89.9 ± 4.4 | 89.7 ± 3.5 | 91.3 ± 2.0 | 86.7 ± 6.2 |  < 0.001 | 0.097 |
Lt. Sylvian fossa | 75.1 ± 16.6 | 80.9 ± 12.1 | 89.4 ± 4.6 | 62.6 ± 22.8 |  < 0.001 |  < 0.001 |
Rt. Sylvian fossa | 72.8 ± 17.4 | 80.2 ± 11.0 | 89.1 ± 5.4 | 63.2 ± 22.2 |  < 0.001 |  < 0.001 |
Lt. Sylvian sulcus (anterior ramus) | 56.0 ± 14.8 | 60.7 ± 12.0 | 69.9 ± 10.6 | 49.4 ± 18.9 |  < 0.001 |  < 0.001 |
Rt. Sylvian sulcus (anterior ramus) | 56.3 ± 14.7 | 65.3 ± 10.7 | 69.6 ± 9.1 | 51.6 ± 18.7 |  < 0.001 |  < 0.001 |
Lt. Sylvian sulcus (posterior ramus) | 69.0 ± 14.2 | 73.9 ± 9.6 | 81.3 ± 5.6 | 56.8 ± 20.1 |  < 0.001 |  < 0.001 |
Rt. Sylvian sulcus (posterior ramus) | 69.1 ± 12.9 | 75.2 ± 9.9 | 80.8 ± 6.4 | 57.1 ± 18.4 |  < 0.001 |  < 0.001 |
Lt. central sulcus | 52.4 ± 13.4 | 54.6 ± 10.0 | 58.8 ± 11.0 | 36.9 ± 10.4 |  < 0.001 | 0.035 |
Rt. central sulcus | 53.7 ± 12.6 | 53.8 ± 9.5 | 56.9 ± 14.0 | 39.9 ± 10.9 |  < 0.001 | 0.347 |
Lt. superior frontal sulcus | 45.6 ± 13.7 | 49.5 ± 10.7 | 55.2 ± 14.1 | 36.6 ± 12.3 |  < 0.001 | 0.008 |
Rt. superior frontal sulcus | 46.1 ± 15.2 | 51.4 ± 10.8 | 57.3 ± 12.0 | 36.6 ± 11.1 |  < 0.001 |  < 0.001 |
Lt. marginal sulcus | 55.8 ± 12.0 | 59.9 ± 11.5 | 59.0 ± 13.5 | 38.7 ± 12.4 |  < 0.001 | 0.140 |
Rt. marginal sulcus | 56.3 ± 12.4 | 59.4 ± 11.1 | 57.0 ± 14.9 | 36.2 ± 12.4 |  < 0.001 | 0.413 |
Interhemispheric fissure (upper part) | 41.5 ± 17.0 | 48.1 ± 16.6 | 54.0 ± 16.7 | 35.2 ± 16.9 |  < 0.001 | 0.011 |
Lamina terminals cistern | 47.6 ± 18.5 | 39.2 ± 16.2 | 37.7 ± 18.3 | 29.3 ± 10.4 | 0.033 | 0.041 |
Interpeduncular cistern | 39.0 ± 11.4 | 34.5 ± 12.6 | 35.0 ± 15.3 | 30.9 ± 13.3 | 0.290 | 0.066 |