Fig. 4From: Age dependent contribution of entry via the CSF to the overall brain entry of small and large hydrophilic markersDextran and sucrose entry into brain and CSF in shorter experiments. Cortex/plasma (filled●) and CSF/plasma (open○) concentration ratios (%) of sucrose and dextran in E16 (A & B) and E19 (C & D) pups. Samples collected 30 s, 1 min or 5 min following i.v. injection of 3H-dextran or 14C-sucrose. Note sucrose but not dextran entry in CSF increased with time in both E16 & E19. Mean ± SD where possible, n = 2–4Back to article page