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Table 1 Demographic and clinical data of enrolled patients

From: The intrathecal, polyspecific antiviral immune response in neurosarcoidosis, acute disseminated encephalomyelitis and autoimmune encephalitis compared to multiple sclerosis in a tertiary hospital cohort

Diagnosis

Multiple sclerosis

Neurosarcoidosis

Autoimmune encephalitis

Acute disseminated encephalomyelitis

n

33

22

19

8

Mean age in years (range; SD)

47.8 (23–73; 11.8)

54.7 (31–83; 15.0)

56.2 (31–84; 16.7)

30.6 (4–63; 17.8)

Gender, females in %

69.7

40.9

36.8

50.0

Additional clinical details

MS types:

 RRMS: n = 14

 SPMS: n = 5

 PPMS: n = 14

Most frequent neurologic/radiologic syndromes:

 myelitis: n = 6

 subcortical cerebral lesions: n = 6

 hydrocephalus: n = 3

 brainstem nerve palsy: n = 3

 meningitis: n = 2

Detected antibodies against:

 VGKC: n = 12

 NMDAR: n = 5

 GAD: n = 2

 GABAB-R :n = 1 (1 patient had VGKC- and NMDAR-antibodies)

Neurologic syndromes in addition to encephalopathy:

 brainstem syndrome: n = 3

 hemisyndrome due to cerebral lesions: n = 3

 cerebellar syndrome: n = 1

 myelitis: n = 1

  1. n number of patients, SD standard deviation, RRMS relapsing-remitting multiple sclerosis, SPMS secondary progressive multiple sclerosis, PPMS primary progressive multiple sclerosis, VGKC voltage-gated potassium channel, NMDAR N-methyl-d-aspartate receptor, GAD glutamic acid decarboxylase GABA B -R γ-aminobutyric acid B receptor