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Table 4 Repeated measures assessment of cystatin C activity

From: Measurement of cystatin C functional activity in the cerebrospinal fluid of amyotrophic lateral sclerosis and control subjects

 

Mean cystatin C concentration (μg/ml) ± SD

Mean assay activity ± SD

Mean cystatin C activity ± SD

Mean activity ratio ± SD

ALS (n = 16)

3.54 ± 1.03

1381 ± 798

3006 ± 652

875 ± 132

DC (n = 16)

3.54 ± 1.05

1476 ± 1009

2939 ± 827

842 ± 149

HC (n = 16)

3.53 ± 1.03

1433 ± 782

3010 ± 691

875 ± 121

p -value

0.597

0.796

0.843

0.859

  1. When samples were paired across groups by CSF cystatin C concentration, there were no significant differences in papain assay activity, cystatin C activity, or cystatin C activity ratio among the three diagnostic groups. Assay activity units are listed as RFU/min.