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Table 3 Comparison of cystatin C concentration, papain assay activity, cystatin C activity, and cystatin C activity ratio among experimental groups

From: Measurement of cystatin C functional activity in the cerebrospinal fluid of amyotrophic lateral sclerosis and control subjects

 

Mean cystatin C concentration ± SD

Mean assay activity ± SD

Mean cystatin C activity ± SD

Mean activity ratio ± SD

ALS (n = 23)

3.09 ± 1.10

1744 ± 919

2663 ± 762

887 ± 131

DC (n = 23)

3.51 ± 1.07

1547 ± 980

2868 ± 850

829 ± 133

HC (n = 23)

3.84 ± 1.13

1302 ± 742

3124 ± 634

843 ± 138

p -value

0.077

0.247

0.124

0.312

  1. For each diagnostic group, the mean cystatin C protein concentration in the CSF (μg/ml), papain inhibitory assay activity in raw CSF, and cystatin C activity in CSF treated with anti-cystatin C antibody are shown. The right column depicts the mean activity ratio determined by dividing the total cystatin C activity by the total cystatin C concentration for each sample. No differences among experimental groups reached statistical significance by one-way ANOVA. Assay activity units are listed in RFU/min.
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Fluids and Barriers of the CNS

ISSN: 2045-8118