Figure 4
From: Protein and synthetic polymer injection for induction of obstructive hydrocephalus in rats
Photomicrographs showing effects of ethylene vinyl alcohol copolymer (Onyx) injection. At low magnification (A; H&E stain), the black tantalum granules in the polymer matrix are obvious in the fourth ventricle (arrow). By 2d (B; H&E stain) multinucleate (foreign body reaction) giant cells are apparent (arrow) adjacent to the Onyx. By 14d (C; H&E stain) the giant cell and fibroblastic reaction is more advanced, surrounding the Onyx clusters. There is associated collagen (green material, arrow) deposition as early as 5d (D; Masson's trichrome stain). Scale Bar (shown in frame D) is 50 μm for B and D, 100 μm for C, and 1600 μm for A.