Table 2 Permeability of verapamil across isolated brain capillary endothelial cells and isolated choroid plexus epithelial cells kept in monolayer cultures.
From: Choroid plexus epithelial monolayers – a cell culture model from porcine brain
mean permeability coefficient (× 10-5cm/sec) | ratio | ||
|---|---|---|---|
Brain capillary endothelial cells | luminal (l) → abluminal (al) | 4.68 | al → l/l → al (brain→blood/blood→brain) 8.27 |
abluminal → luminal | 38.70 | ||
CP epithelial cells | apical (a) → basolateral (b) | 11.65 | a → b/b → a (CSF→blood/blood→CSF) 1.22 |
basolateral → apical | 9.55 |